Tenormin is used in the management of high blood pressure (hypertension), control over irregular heartbeat (arrhythmia) as well as for relief of recurrent chest pain episodes (angina pectoris). The medicine also protects patients who have had a heart attack (myocardial infarction) in the past and prevents another one.
Tenormin is composed of the active ingredient Atenolol, a beta-adrenoceptor blocking medicine, often referred to as a beta-blocker. This medication works on the heart and blood vessels, causing the heart to beat slower and with less force. This way, the blood pressure within the blood vessels is reduced, making it easier for the heart to pump blood around the body.
The blood-lowering effect of the drug helps decrease the risk of cardiovascular complications, primarily strokes and myocardial infarctions, as well as manage uneven heart rhythms in patients with arrhythmia. Tenormin lessens the pressure exerted on the heart, which also helps reduce the number and duration of anginal attack in those having angina pectoris.Atenolol is a synthetic and cardioselective beta-adrenoceptor blocking agent which exerts antihypertensive, hypotensive, and antiarrhythmic effects. It acts primarily on beta-1 adrenergic receptors located in the heart and the vascular smooth muscle. The active ingredient works by competing with sympathomimetic neurotransmitters like catecholamines for binding to the receptors site where it inhibits sympathetic stimulation. This causes a reduction in myocardial contractability and heart rate as well as lowers blood pressure. If the medicine is taken at higher doses, it also can competitively block beta-2 adrenergic responses in the bronchial and vascular smooth muscles. Atenolol’s administration also leads to a decrease in myocardial oxygen consumption, which is beneficial for the prevention of recurrent episode of chest pain (angina pectoris) and their severity.